Клинические исследования

12-недельное клиническое исследование приёма курса коллагена с участием 43 женщин-добровольцев. Двойное слепое, плацебо-контролируемое исследование, оценивающее следующие преимущества: увлажнение, упругость, эластичность, морщины, сияние и другие параметры, связанные с состоянием кожи.

Torres EAFS, Pinaffi-Langley ACDC, Figueira MS, Cordeiro KS, Negrão LD, Soares MJ, da Silva CP, Alfino MCZ, Sampaio GR, de Camargo AC. Effects of the consumption of guarana on human health: A narrative review. Compr Rev Food Sci Food Saf. 2022 Jan;21(1):272-295.

Wu M, Cronin K, Crane JS. Biochemistry, Collagen Synthesis. 2021 Sep 13. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan--. PMID: 29939531

Chessa MA et al. Dermatol Ther (Heidelb). 2020 Feb;10(1):15-27. doi: 10.1007/s13555-019-00338-x.

Xia, L., Xu, C., Huang, K., Lu, J., & Zhang, Y. (2019). Evaluation of phenolic compounds, antioxidant and antiproliferative activities of 31 grape cultivars with different genotypes. Journal of food biochemistry, 43(6), e12626.

Akbari M, Lankarani KB, Tabrizi R, Ghayour-Mobarhan M, Peymani P, Ferns G, Ghaderi A, Asemi Z. The Effects of Curcumin on Weight Loss Among Patients With Metabolic Syndrome and Related Disorders: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Front Pharmacol. 2019 Jun 12;10:649.

Choi, F.D.; Sung, C.T.; Juhasz, M.L.; Mesinkovsk, N.A. Oral Collagen Supplementation: A Systematic Review of Dermatological Applications. J. Drugs. Dermatol. 2019, 18, 9--16.

A. Jawed, G. Singh, S. Kohli, A. Sumera, S. Haque, R. Prasad, D. Paul, Therapeutic role of lipases and lipase inhibitors derived from natural resources for remedies against metabolic disorders and lifestyle diseases, South African Journal of Botany, Volume 120, 2019, Pages 25-32.

Sodagam L, et al. Front Genet. 2019 Feb 21;10:81. doi: 10.3389/fgene.2019.00081.

Ogawa Y, Kinoshita M, Shimada S, Kawamura T. Zinc and Skin Disorders. Nutrients. 2018 Feb 11;10(2):199. doi: 10.3390/nu10020199. PMID: 29439479; PMCID: PMC5852775.

Egoumenides L, Gauthier A, Barial S, Saby M, Orechenkoff C, Simoneau G, Carillon J. A Specific Melon Concentrate Exhibits Photoprotective Effects from Antioxidant Activity in Healthy Adults. Nutrients. 2018 Mar 31;10(4):437.

Bizot, V., Cestone, E., Michelotti, A., & Nobile, V. (2017). Improving skin hydration and age-related symptoms by oral administration of wheat glucosylceramides and digalactosyl diglycerides: A human clinical study. Cosmetics, 4(4), 37.

Pullar J.M., Carr A.C., Vissers M.C.M. The roles of vitamin C in skin health. Nutrients. 2017; 9:866--892.

Patel DP, Swink SM, Castelo-Soccio L. Skin Appendage Disord. 2017 Aug;3(3):166-169. doi: 10.1159/000462981.

Ou J, et al. Food Chem. 2017 Apr 15;221:1057-1061.

Daily, J. W., Yang, M., & Park, S. (2016). Efficacy of Turmeric Extracts and Curcumin for Alleviating the Symptoms of Joint Arthritis: A Systematic Review and Meta-Analysis of Randomized Clinical Trials. Journal of medicinal food, 19(8), 717--729.

Schunck M, Zague V, Oesser S, Proksch E. Dietary Supplementation with Specific Collagen Peptides Has a Body Mass Index-Dependent Beneficial Effect on Cellulite Morphology. J Med Food. 2015 Dec;18(12):1340-8.

Costa, A., Pegas Pereira, E. S., Assumpção, E. C., Calixto Dos Santos, F. B., Ota, F. S., de Oliveira Pereira, M., Fidelis, M. C., Fávaro, R., Barros Langen, S. S., Favaro de Arruda, L. H., & Abildgaard, E. N. (2015). Assessment of clinical effects and safety of an oral supplement based on marine protein, vitamin C, grape seed extract, zinc, and tomato extract in the improvement of visible signs of skin aging in men. Clinical, cosmetic and investigational dermatology, 8, 319--328.

Brescoll J, Daveluy S. Am J Clin Dermatol. 2015 Feb;16(1):27-33. doi: 10.1007/s40257-014-0107-3. PMID: 25559140.

Gupta M, Mahajan VK, Mehta KS, Chauhan PS. Zinc therapy in dermatology: a review. Dermatol Res Pract. 2014;2014:709152. doi: 10.1155/2014/709152. Epub 2014 Jul 10. PMID: 25120566; PMCID: PMC4120804.

Butt MS et al. Crit Rev Food Sci Nutr. 2013;53(9):875-86. doi: 10.1080/10408398.2011.571799. PMID: 23768180.

Papakonstantinou E, Roth M, Karakiulakis G. Hyaluronic acid: A key molecule in skin aging. Dermatoendocrinol. 2012;4(3):253-258. doi:10.4161/derm.21923

Capodice JL. J Cosmet Dermatol Sci Appl. 2012;2:132–5.

Kato, Norihisa. (2012). Role of vitamin B6 in skin health and diseases. 10.3920/978-90-8686-729-5_4.

Heinrich, U.; Moore, C.E.; De Spirt, S.; Tronnier, H.; Stahl,W. Green tea polyphenols provide photoprotection, increase microcirculation, and modulate skin properties of women. J. Nutr. 2011, 141, 1202--1208.

Barel, A., Calomme, M., Timchenko, A., De Paepe, K., Demeester, N., Rogiers, V., Clarys, P., & Vanden Berghe, D. (2005). Effect of oral intake of choline-stabilized orthosilicic acid on skin, nails and hair in women with photodamaged skin. Archives of dermatological research, 297(4), 147--153.

Maalouf S, El-Sabban M, Darwiche N, Gali-Muhtasib H. Protective effect of vitamin E on ultraviolet B light-induced damage in keratinocytes. Mol Carcinog. 2002;34:121--30.

Musalmah M, Fairuz AH, Gapor MT, Ngah WZ. Effect of vitamin E on plasma malondialdehyde, antioxidant enzyme levels and the rates of wound closures during wound healing in normal and diabetic rats. Asia Pac J Clin Nutr. 2002;11 Suppl 7:S448-451. (PubMed)

L. Incandela, M.R. Cesarone, M. Cacchio, M.T. DeSanctis, C. Santavenere, and M.G. D'Auro,"Total triterpenic fraction of Centella asiatica in chronic venous insufficiency and in high perfusion microangiopathy,"Angiology, vol. 52, pp.9--13,2001.

Badmaev V, Majeed M, Prakash L. J Nutr Biochem. 2000 Feb;11(2):109-13. doi: 10.1016/s0955-2863(99)00074-1. PMID: 10715596.

Shoba G et al. Planta Med. 1998 May;64(4):353-6. doi: 10.1055/s-2006-957450. PMID: 9619120.

Meyer LJ, Stern R. J Invest Dermatol 1994; 102:385-9; PMID:8120424.